Practical aspects of NMR signal assignment in larger and challenging proteins
نویسندگان
چکیده
منابع مشابه
Practical Aspects of Quantitative NMR Experiments
This discussion presumes that you already have an understanding of the basic theory of NMR. There are a number of issues that should be considered when measuring NMR spectra for quantitative analysis. Many of these issues pertain to the way that the NMR signal is acquired and processed. It is usually necessary to perform Q-NMR measurements with care to obtain accurate and precise quantitative r...
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پس از بررسی هر کدام از فاکتورهای نوع صنعت, نوع ضمانت نامه, نرخ بهره , نرخ تورم, ریسک اعتباری کشورها, کارمزد, ریکاوری, gdp, پوشش و وثیقه بر ریسک اعتباری صندوق ضمانت صادرات ایران مشخص گردید که همه فاکتورها به استثنای ریسک اعتباری کشورها و کارمزد بقیه فاکتورها رابطه معناداری با ریسک اعتباری دارند در ضمن نرخ بهره , نرخ تورم, ریکاوری, و نوع صنعت و ریسک کشورها اثر عکس روی ریسک اعتباری داردو پوشش, وثی...
15 صفحه اولNMR structure determination for larger proteins using backbone-only data.
Conventional protein structure determination from nuclear magnetic resonance data relies heavily on side-chain proton-to-proton distances. The necessary side-chain resonance assignment, however, is labor intensive and prone to error. Here we show that structures can be accurately determined without nuclear magnetic resonance (NMR) information on the side chains for proteins up to 25 kilodaltons...
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Functional MR imaging (fMRI) based upon the Blood Oxygen Level Dependent (BOLD) effect is currently an important new tool for understanding basic brain function and specifically allowing the correlation of physiological activity with anatomical location without the use of ionizing radiation. The clinical role of fMRI is still being defined and is the subject of much research activity. In this r...
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The 6-dimensional (6D) APSY-seq-HNCOCANH NMR experiment correlates two sequentially neighboring amide moieties in proteins via the C' and Calpha nuclei, with efficient suppression of the back transfer from Calpha to the originating amide moiety. The automatic analysis of two-dimensional (2D) projections of this 6D experiment with the use of GAPRO (Hiller et al., 2005) provides a high-precision ...
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ژورنال
عنوان ژورنال: Progress in Nuclear Magnetic Resonance Spectroscopy
سال: 2014
ISSN: 0079-6565
DOI: 10.1016/j.pnmrs.2013.12.001